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Paula Hammond, an MIT Institute Professor, head of the Department of Chemical Engineering, and a member of the Koch Institute

Given the vicious circle between ROS production and mitochondrial dysfunction mentioned above, it has been reasonably hypothesized that, in some individuals with pre-existing sub-optimal mitochondrial function, an infection can tip the host into a chronic and self-perpetuating metabolically imbalanced non-resolving state characterized by mitochondrial dysfunction, where ROS continually drive inflammation (204)

Arab J Chem 13:65896597

doi: 10.1016/j.ecoenv.2023.115112 53

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